(R)-Diisopropyl 2-hydroxysuccinate - Names and Identifiers
(R)-Diisopropyl 2-hydroxysuccinate - Physico-chemical Properties
Molecular Formula | C10H18O5
|
Molar Mass | 218.25 |
Density | 1.055g/mLat 25°C(lit.) |
Boling Point | 237°C(lit.) |
Flash Point | >230°F |
Vapor Presure | 0.000105mmHg at 25°C |
pKa | 12.45±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.43(lit.) |
(R)-Diisopropyl 2-hydroxysuccinate - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
(R)-Diisopropyl 2-hydroxysuccinate - Introduction
diisopropyl (R)-( )-malate, chemical formula C9H14O5, is a diester compound of malic acid. It is a colorless to pale yellow liquid with an apple-like aroma. The following is a description of the nature, use, formulation and safety information of diisopropyl (R)-( )-malate:
Nature:
-Appearance: Colorless to light yellow liquid
-Density: about 1.09g/cm³
-Boiling point: about 208-210°C
-Refractive index: about 1.429-1.431
Use:
-Chemical synthesis: As an important starting material for the synthesis of organic compounds, it is widely used in the fields of drugs, pesticides and spices.
Preparation Method:
the preparation method of diisopropyl (R)-( )-malate is generally realized by esterification reaction, and the specific steps are as follows:
1. Add malic acid and isopropanol to the reaction vessel.
2. Add a small amount of acid catalyst, such as sulfuric acid, thionyl chloride, etc.
3. The reaction is carried out at an appropriate temperature and reaction time.
4. Through distillation and purification steps, pure diisopropyl (R)-( )-malate product is obtained.
Safety Information:
diisopropyl (R)-( )-malate is generally considered a relatively safe chemical, there are still some caveats:
-Avoid prolonged contact with skin and eyes to avoid irritation or damage.
-Wear appropriate personal protective equipment such as gloves and goggles when using.
-Avoid generating steam or dust and ensure a well-ventilated operating environment.
-Store away from high temperature, fire and oxidizing agents, and ensure that the container is well sealed.
-In the event of accidental splashing or mistaking, wash or rinse your eyes immediately and seek medical help.
Last Update:2024-04-09 15:18:00